Masoud Khorrami-Nejad1,2, Mehdi Khodaparast1 , Ihsan Ali Abdulkadhim2 , Elham Azizi3 , Fatemeh Rashidi1 , Vahid Damanpak1 and Hesam Hashemian1,4*
*Correspondence: Hesam Hashemian shhlucky@yahoo.com
1 Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
2 School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Optometry and Vision Sciences, University of Melbourne, Melbourne, Australia
4 Farabi Eye Hospital, Tehran University of Medical Sciences, Kargar Street, Tehran, Iran
Purpose To assess the level of agreement and evaluate the reliability of measurements between two Scheimpflug imaging modalities, Scansys (MediWorks, China) and Sirius (CSO, Italy), in quantifying the anterior segment parameters in healthy eyes.
Methods In a cross-sectional study, the right eyes of 38 healthy participants without any ocular or systemic diseases were examined. A range of anterior segment parameters including anterior and posterior flat and steep keratometry, central corneal thickness (CCT), thinnest corneal thickness (TCT), anterior chamber depth (ACD), anterior chamber angle (ACA), corneal volume, anterior chamber volume, and horizontal white to white diameter, derived from the sagittal curvature maps were measured. To evaluate the reliability of the measurements, intraclass correlation coefficient (ICC) and correlation coefficient were measured. Additionally, Bland-Altman plots were employed to examine the agreement in mean (bias line) and 95% limits of agreement between the two devices.
Results The mean age was 31.5±6.9 (range: 19–47) years. The ICC indicated that the majority of anterior segment parameters had an excellent or good level of reliability, surpassing the threshold of 0.9. Nevertheless, CCT and ACA exhibited a moderate level of reliability, with ICC values of 0.794 and 0.728, respectively. The correlation analysis showed a strong correlation for all the variables tested. The Bland-Altman plots revealed that the bias line was near zero and the 95% limits of agreement were narrow for most variables, except for the anterior flat and steep keratometry, which were found to range from −0.57 to 0.84 D and −0.68 to 0.87 D, respectively.
Conclusion Scansys and Sirius devices can be effectively used interchangeably for the evaluation of most anterior segment parameters; however, for anterior corneal curvatures, CCT and ACA, their alternative use is not recommended.
Masoud Khorrami-Nejad, et al. A comparison of Scansys and Sirius tomography in healthy eyes.pdf
